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Cymbalta and agresssive personality

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Posted: 06/10/07 - 21:02
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cheri5
Joined: 10 Jun 2007

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My Mom has been depressed since my Dad passed away in 2005 . She has been on various antidepressents the last being Celexa. They increased it to 40 mg and she got tremors and increased anxiety. She is now taking Cymbalta. What I have noticed is now she is very confrontationale and has an agressive demeanor. I'm looking at it as a good thing my husband doesn't think it is good. I was thinking she now has an opinon. Example I asked if she wanted to come for dinner. "Normally" no matter what time she would just stop what she was doing and I would go over and get her. She is also mad at a friend for what I think is not justified. She wouldn't normally be mad with anthying this friend did, I can't see why she is angry except for this medication.
Has anyone seen a personality change toward the aggressive end?


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Posted: 11/26/07 - 11:10
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yes my mom is shows signs of aggression. she also repeats herself three times. So now she complains about my father three times in the same conversation.
these people need friends excercise and sunshine.


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Posted: 01/28/08 - 10:17
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I am 37 years old and have been on Cymbalta since the birth of my second child, four years ago. I recently decided the wieght gain must be from the Cymbalta since I have never been over weight and very athletic and now I keep gaining and gaining. I have tried to stop taking the Cymbalta but one dose missed causes so much discomfort I cant seem to get off. I have headaches, dizzyness, tingling in my face, flu like symptoms, vision problems. unsteady on my feet, speak is messed up-I cant seem to say what I want to say. I am so sick and angry all the time. I have become more aggressive since taking the meds and trying to get off of it is even worse!!!

I need help!! I need to get off this stuff but can not manage to work with the withdrawal symptoms. Any suggesstions?


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Posted: 11/24/08 - 18:00
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Eddie39
Joined: 24 Nov 2008

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I have been on cymbalta 60mg for a month now, before that I was on efexor 150mg for five years. My doctor wanted to change the meds due to my weight gain and other meds for underactive thyroid. I am on cymbalta for bipolar II disorder. I have felt alive for the first time in years. I am actually interested in things, am drawing again and listening to music. Sounds great BUT....I feel aggressive, have had outbursts of rage, my children have said I am more irritable, I am very confrontational. My doctor wants me to switch back to efexor which I can see i will need to do, I know I will have to. Whilst I don't want to go back to zombie land with efexor, I know the cymbalta may take me down a road which is not healthy for anyone.


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Posted: 06/22/09 - 05:45
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I'm sorry those of you posting here are experiencing aggression as a side effect of Cymbalta but am grateful to you for posting about it. My dad's been treated for depression for several years and I lost track of what he was taking. Recently, he's become a raging bully; I can't say it's a personality change but it's certainly a frightening intensification of his former personality, minus his good qualities. He's become loud, embarrassing, irrational and verbally aggressive. Truly over-the-top. I thought it was a form of dementia, but just found out he's now taking Cymbalta. (I'd checked the side effects for what he used to take and didn't find reports of agression like the posters here have mentioned). I've also read reports that Cymbalta doesn't increase aggression but I'm pretty convinced from the few posts here and seeing the drastic change in my dad that it absolutely can. Thank you again for posting your experiences. I feel better armed to help him, now.


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