What are Actinomycin D effects on Nucleic Acids during Tumor Regression?

riane1742 · Newbie Joined: 11 Jul 2006 Posts: 1

Hello, my mother is 67 years old and she has a breast cancer. I cannot explain how awful I feel when I look at her. And she has been prescribed with Actinomycin D and I would like to know what it does. What are its effects on Nucleic Acids during Tumor Regression?

marybeth477 · Newbie Joined: 28 Aug 2007 Posts: 1

Actinomycin is anti cancer antibiotic isolated from bacteria sreptomyces. It attaches itself firmly to DNA, between neighboring pairs (guanine and cytosine). It inhibits all forms of enzymes that are engaged in the process of creating RNA in tumor cells. As for side effects there is depression of bone marrow, nausea, vomiting, diarrhea, skin rash, alopecia…

What are Actinomycin D effects on Nucleic Acids during Tumor Regression?

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