Possible causes of epilepsyNot all the causes of epilepsy are known, but many predisposing factors have been identified, including:
- brain damage resulting from malformations during brain development,
- head trauma,
- neurosurgical operations,
- penetrating wounds of the brain,
- brain tumor, high fever,
- bacterial or viral encephalitis,
- acute or inborn disturbances of metabolism,
- chemical disturbances of the brain - drugs or poisons or organs that don't work properly.
- an inherited tendency to seizures.
- sleep loss.
- sudden stopping of drugs
Hereditary or genetic factors also play a role - mutations in several genes have been linked to some types of epilepsy. Some genes that code for protein subunits of voltage-gated and ligand-gated ion channels have been associated with forms of generalized epilepsy and infantile seizure syndromes.