Your doctor prescribed you good drug, if hypertension is your problem. However, you need to know, that Avapro is contraindicated in patients who are hypersensitive to any component of this product. For male and female rats, 500 mg/kg/day provided an average systemic exposure to ibesartan. Average systemic exposure was in humans receiving the maximum recommended dose of 300 mg
irbesartan/day. Irbesartan was negative in severall tests for induction of chromosomal aberrations. You should be sure that Avapro might be administered with other antihypertensive agents. Avapro may be administered with or without food, so this is also something that should not be worrying you. Avapro is an orally active agent that does not require
biotransformation into an active form. The oral absorption of Avapro is rapid and complete with an average absolute bioavailability of 60-80%. I hope this would satisfy your wish to learn more about this medicine, and I would recommend you to stop be suspicious to your doctor, because he knows his job.
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