At 64 years old I began cymbalta about 1 year ago, and experienced both constipation and regurgitation. I now take 80 mgs, and have virtually no constipation. However, I accomplished this by taking several health supplements such as "ColonCleanse" fish oil, flax oil, omega 3 oil. Further, I completely stay away from simple carbohydrates, exercise and eat fruits and vegetables. Occasionally I use gelatin suppositories.
I do believe that cybalta does have a beneficial effect on my severe depression and resultant lethargy. I am way less depressed, more alert and energetic.
Unfortunately, I drink six or more ounces of vodka each night, drink wine with dinner, and if I over do it even slightly, I am terribly sick in the morning. I am told that if I keep drinking, I will likely start having seizures. My sex drive sucks. I will have to get real about all this.
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