3' 5' exonuclease

See

From the data presented it can be concluded that the cryptic 3'-5' exonuclease is the only exonucleolytic activity associated with the viral DNA polymerase.
The lack of 3'-5' exonuclease is very important since it is not advantageous to have the enzyme remove the terminal ddNTP and continue elongation.
In this context, the thermostable 3'-5' exonuclease is more active at temperatures between 37.
These studies showed that the function of the 3'-5' exonuclease is to prevent misincorporation during DNA replication and to prevent mutations.
0 (Saint Louis) Home | Analyze a sequence | Browse Pfam | Keyword search | Taxonomy search | Swisspfam | Help 3HCDH_N 4F5 3_5_exonuc Accession number: PF01612 3'-5' exonuclease This domain is responsible for the 3'-5' exonuclease proofreading activity of E.
elegans Y2H interaction GO Term GO DAG Tree Display XML Schema Acedb ImageGene Ontology Summary for term: GO:0008408Details ID: GO:0008408Term: 3'-5' exonuclease activityDefinition: Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
In addition to its AP (apurinic/apyrimidinic) endonucleolytic function, APE1 possesses 3' phosphodiesterase and 3'-5' exonuclease activities.

Would you like to discuss or post question about 3' 5' exonuclease ? Click here !