5HT transporter

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serotonin transporter

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• Additionally, the 5HT transporter is differentially regulated by second messengers since direct activation of protein kinase C by phorbol esters decreases 5HT uptake by decreasing Vmax.
• Page 14 14 Pinelopi Lundquist The 5HT transporter is the target for the widely prescribed drug class of SSRIs that increase 5HT neurotransmission but decrease the activity of the 5HT neuron itself (Fuller 1994; White et al.
• No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder.
• Rats with constitutionally upregulated/downregulated platelet 5HT transporter: differences in anxiety-related behavior.
• The brain 5HT transporter appears to be a principal site of action of therapeutic antidepressants and may mediate behavioral and/or toxic effects of cocaine and amphetamines.
• There has also been a major focus on 5HT transporter polymorphisms.
• Aim: To investigate the association between depression and 5HT transporter re-uptake binding in DLB patients.

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