5 alpha reductase

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Type-1 steroid 5 alpha-reductase is functionally active in the hair follicle as evidenced by new selective inhibitors of either type-1 or type-2 human steroid 5 alpha-reductase.
Activity of type 1 5 alpha-reductase is greater in the follicular infrainfundibulum compared with the epidermis.
) 5-alpha-reductase is necessary for the conversion of testosterone into dihydrotestosterone.
The enzyme 5 alpha reductase is thought to be the major cause of this.
Endocrine manipulation experiments were designed to determine whether 5 alpha-reductase is regulated at the steady state mRNA level.

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