5 bromouracil

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On the basis of all of these calculated results, a new mutagenic mechanism for the A-T to G-C transition induced by 5-bromouracil is described in detail for the first time.
An increased abundance of enol tautomers when passing from uracil to 5-bromouracil is not supported by our calculations.
5-Bromouracil is coordinated to the metal ion through the O atom of C(4)=O and the N atom of N(1), while histidine coordinates through the O atom of —CO2- and the N atom of the —NH2 groups.
5-Bromouracil is almost identical to thymine and gets incorporated into DNA in place of thymine.
5-Bromouracil 5-Bromouracil 5-Bromo-2,4(1H,3H)-pyrimidinedione 5-bromo uracil 5-Bromouracil (5-Bromo-2,4-dihydroxypyrimidine) 5-Bromo-2,4-(1H,3H)-pyrimidinedione 5-Bromouracil 5-Bromo-2,3-dihydroxypyrimidine 5-bromopyrimidine-2,4-diol RN: 51-20-7 MF: C4 H3 Br N2 O2 C4H3BrN2O2 C4H3BrN2O2 MW: 190.
5-Bromouracil Wikipedia 5-Bromouracil 5-Bromouracil Chemical name 5-Bromouracil Chemical formula C4H3BrN2O2 Molecular mass 191.
Phagocytes Produce 5-Chlorouracil and 5-Bromouracil, Two Mutagenic Products of Myeloperoxidase, in Human Inflammatory Tissue* Jeffrey P.
Replication of DNA containing 5-bromouracil can be mutagenic in Syrian hamster cells.
5, 457-464 Sensitization of Escherichia coli C to gamma-radiation by 5-bromouracil incorporation THOMAS BONURA and KENDRIC C .

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