6 thioguanine
From Health Encyclopedia
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Broader Terms
6 thiopurine, antineoplastic, guanine analog
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Facts (generated by robot; please edit if you find it inaccurate)
- Designing Drugs: Gertrude Elion, on Invention and Technology 6-Thioguanine say: 6-thigh-oh-GWAN-een 6-Thioguanine is closely related to 6-mercaptopurine, both in structure (see above) and in metabolism.
- 282, Issue 2, 1102-1108, 1997 Tissue Specific Toxicities of the Anticancer Drug 6-Thioguanine Is Dependent on the Hprt Status in Transgenic Mice1 Jiri Aubrecht, Mary E.
- : 6-Thioguanine is a purine analog primarily indicated for acute myelogenous leukemia.
- Our results show that 6-thioguanine is an effective inhibitor of chlamydial growth with either wild-type or hypoxanthine-guanine phosphoribosyltransferase-deficient cell lines as the host.
- Conclusions 6-Thioguanine is effective for the treatment of moderate to severe plaque-type psoriasis, and may be safe when given for defined periods and with careful hematologic monitoring.
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