AChE

See

acetylcholinesterase

Facts

AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane.
AChE is found in nerves and muscles and operates by rapidly binding to and hydrolyzing (breaking apart) ACh, which is a neurotransmitter.
AChE is thus the essential "off switch" for signal transmission across nerve synapses.
Expression of AChE can represent a marker of skeletal muscle differentiation.

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