Anaphase
From Health Encyclopedia
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Facts (generated by robot; please edit if you find it inaccurate)
- The onset of anaphase is triggered by specific biochemical changes that occur to regulate the division cycle through modulation of the enzyme cascade responsible for cell-wide protein phosphorylation.
- Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase.
- The motor for poleward chromosome movement in anaphase is in or near the kinetochore.
- Anaphase is preceded by metaphase, by the end of which fully condensed sister chromatids are arranged in pairs in the spindle midzone, defining a structure referred to as the metaphase plate.
- All the chromosomes are able to coordinate the breaking of their centromeres quite well and the speed at which the chromatids move is impressive so anaphase is a sight to see! (In a living cell, of course.
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