Anaphylatoxin
From Health Encyclopedia
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Broader Terms
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Related Terms
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Scope Note
complement peptides (C3a and C5a) which cause mast cell degranulation and smooth muscle contraction.
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Facts (generated by robot; please edit if you find it inaccurate)
- C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease.
- Receptor for the C3a anaphylatoxin is expressed by neurons and glial cells.
- Functionderived from proteolytic degradation of complement c5, c5 anaphylatoxin is a mediator of local inflammatory process.
- Functionderived from proteolytic degradation of complement c3, c3a anaphylatoxin is a mediator of local inflammatory process.
- Comments FUNCTION: Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process.
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