Antigen receptor

From Health Encyclopedia

Contents 1 Broader Terms 2 Narrower Terms 3 Related Terms 4 Scope Note 5 Facts (generated by robot; please edit if you find it inaccurate)

Broader Terms

cytoplasmic receptor

Narrower Terms

B cell receptor, T cell receptor

Related Terms

CD14 molecule

Scope Note

family of immunoglobin-like lymphocyte surface molecules that mediate activation of lymphocytes by antigens.

Facts (generated by robot; please edit if you find it inaccurate)

• Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130.
• Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia.
• Signal Transduction through the B Cell Antigen Receptor Is Normal in Ataxia-Telangiectasia B Lymphocytes* Peter Speck, Masato Ikeda, Akiko Ikeda, Howard M.
• Syk Activation and Dissociation from the B-cell Antigen Receptor Is Mediated by Phosphorylation of Tyrosine 130* (Received for publication, February 13,1997) Lakhu M.
• Receptor: The B cell antigen receptor is composed of two immunoglobulin (Ig) heavy chains, initially of the mu isotype (AfCS # A001181), two Ig light chains (kappa, #A001163 or lambda, #A001164) and the associated molecules Ig alpha (CD79a, #A000586) and Ig beta (CD79b, #A000587).

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