Antiphospholipid syndrome

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Contents

Used for

antiphospholipid antibody syndrome

Broader Terms

autoimmune disorder, syndrome

Related Terms

systemic lupus erythematosus

Scope Note

associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses; involves the presence of antibodies directed against phospholipids; cardiolipins show markedly elevated levels of anticardiolipin antibodies; present also are high levels of lupus anticoagulant; in pregnancy it can cause abortion.

Facts (generated by robot; please edit if you find it inaccurate)

  • Discussion: Antiphospholipid Syndrome Antiphospholipid syndrome is defined as the presence of antiphospholipid antibodies, arterial or venous thrombosis, recurrent spontaneous abortions, and thrombocytopenia.
  • En Espaol | Complete disclaimer 19ee Antiphospholipid Syndrome What is Antiphospholipid Syndrome? Antiphospholipid Syndrome is a disorder in which the blood clotting system begins to form blood clots in the veins or arteries without obvious reason.
  • To avoid further confusion, antiphospholipid syndrome is currently the preferred term for this clinical syndrome.
  • eduAntiphospholipid syndrome is a hypercoaguable state characterized by recurrent venous and/or arterial thrombosis and/or pregnancy complications of fetal loss, pre-eclampsia, or eclampsia in the presence of antiphospholipid antibodies.
  • It is now generally accepted that the antiphospholipid syndrome is the result of dimerization of 2-glycoprotein I due to binding of the antibodies.

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