Antithrombin

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Broader Terms

anticoagulant

Narrower Terms

antithrombin III, fibrin, heparin

Facts (generated by robot; please edit if you find it inaccurate)

  • Antithrombin is a plasma protein with anticoagulant and anti-inflammatory properties that, like many other therapeutic proteins which are currently derived from the human blood supply, has been difficult to express using conventional recombinant protein production methods.
  • The heparin-binding site of antithrombin is crucial for antiangiogenic activity.
  • "Antithrombin deficiency" (="antithrombin III deficiency" = ATIII deficiency") can be due to 3 reasons: Incorrect diagnosis Inherited deficiency Acquired deficiency What is Antithrombin? Antithrombin is a protein in our blood stream.
  • A disulfide bond in antithrombin is required for heparin-accelerated thrombin inactivation.
  • The antithrombin activity test is performed first, to evaluate whether antithrombin is functioning normally.

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