Apo B

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apolipoprotein B

Facts (generated by robot; please edit if you find it inaccurate)

• 1 Less than 1% of the total apo B is in the chylomicron (apo B48) form.
• In the intima, Apo B is higher than Apo A2, the media contains hardly any Apo B, and the adventitia has less B than A2.
• Apo B is incorporated into VLDL by hepatocytes, preparing this lipoprotein for transport of triglycerides (TG) and cholesterol from liver to other tissues.
• Apo B is the mandatory constituent of LDL particles.
• Apo B is therefore a convenient marker for assessing the cholesterol depositing capacity of the blood, and studies have clearly indicated it as a better discriminator of angiographically documented coronary artery disease than LDL cholesterol.

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