Arachidonate

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Contents

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See for

lipoxin

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Broader Terms

leukotriene

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Narrower Terms

anandamide

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Related Terms

second messenger

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Scope Note

polyunsaturated 20-carbon essential fatty acid found in animal fat or formed in biosynthesis from dietary linoleic acid; also, its salts, esters, or anions; precursor in the biosynthesis of leukotrienes, prostaglandins, and thromboxanes.

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Facts (generated by robot; please edit if you find it inaccurate)

  • The fatty acid arachidonate is frequently esterified at the hydroxyl on C-2 of glycerophospholipids, especially phosphatidyl inositol, shown at right with arachidonate in blue.
  • Relaxation of guinea-pig tracheal smooth muscle to arachidonate is converted to contraction following epithelium removal.
  • Ethyl arachidonate is the predominant fatty acid ethyl ester in the brains of alcohol-intoxicated subjects at autopsy.
  • Arachidonate is 20:4 ( 5, 8, 11, 14 ) in the shorthand notation for unsaturated fatty acids.
  • Arachidonate is released from action of phospholipase A2 or phospholipase C on specific phospholipids (Called Stage 1 of synthesis).
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