Autocrine
From Health Encyclopedia
Contents |
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Broader Terms
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Related Terms
growth factor, hormone regulation /control mechanism
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Scope Note
one of three fundamental types (with paracrine and endocrine) of cellular regulation by intercellular diffusible factors, where the diffusible factor exerts a regulatory influence primarily on the same cell that secreted it.
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Facts (generated by robot; please edit if you find it inaccurate)
- (2000) Endothelin-1 autocrine is suppressed in HeLa cells induced to a senescent state.
- Neutralization experiments demonstrated that the IL-1 alpha autocrine is largely responsible for controlling both collagenase and IL-8 synthesis in repair fibroblasts, as it is in early-passage fibroblasts.
- AT II autocrine is not involved in hypoxic proliferation of PASMCs, but a decrease of AT II may contribute to prevention of the development of HPH.
- Autocrine is a cell signaling to itself.
- HeatherR03-19-1999, 05:18 AMWithout a good medical dictionary it can be hard to get good, clear definitions, and the difference between paracrine and autocrine is a prime example! Few non-med students (including premeds, grad students,.
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