Autoimmune inflammatory bowel disease

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Crohn's disease, inflammatory bowel disease, ulcerative colitis

Facts (generated by robot; please edit if you find it inaccurate)

  • The Company also announced plans to initiate a Phase I/II clinical trial of this antibody in Crohn's disease, an autoimmune inflammatory bowel disease.
  • However, in TNBS-induced colitis, a model for Th1-mediated and autoimmune inflammatory bowel disease, blocking CD40/CD40L interactions prevents the induction phase of the disease but has no effect on the disease after the onset (19).
  • The company also announced plans to initiate a Phase I/II clinical trial of this antibody in Crohn's disease, an autoimmune inflammatory bowel disease.

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