Band 3 protein

From Health Encyclopedia

Broader Terms

membrane protein, membrane transport protein

Facts (generated by robot; please edit if you find it inaccurate)

• The anion-exchange band 3 protein is the main erythrocyte protein that is phosphorylated by tyrosine kinase.
• Band 3 protein is a major erythrocyte transmembrane glycoprotein.
• This shows that monomeric band 3 protein is able to transport anions and that dimerization of the protein does not change its transport activity.
• Cellular localisation Cell Membrane and Cytoplasmic Research areas Cardiovascular >> Blood >> RBC Antigens Relevance The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes.
• Erythroid band 3 protein is a member of a family of three anion exchangers AE1, AE2 and AE3 expressed in a variety of tissues.

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