Behavioral sensitization

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behavioral habituation /sensitization

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  • " Behavioral sensitization is the opposite of tolerance; it is even known as "reverse tolerance.
  • Nicotine-induced behavioral sensitization is associated with extracellular dopamine release and expression of c-Fos in the striatum and nucleus accumbens of the rat.
  • The development of cocaine-induced behavioral sensitization is affected by discrete quinolinic acid lesions of the prelimbic medial prefrontal cortex.
  • Behavioral sensitization is used as a model to study learning and memory, bipolar disorder, and drug abuse.
  • Behavioral sensitization is one of the experimental markers to indicate the potential of a drug to produce dependence [25-27].

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