Bioavailability of drug

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pharmacokinetics

Facts (generated by robot; please edit if you find it inaccurate)

• In short, the oral absorption and hence bioavailability of drug is determined by the extent of drug solubility and permeability.
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• To predict interactions, scientists are looking at enzyme induction, when elevated expression and decreased clearance and bioavailability of drug is seen.
• We further assume that oral bioavailability of drug is 100%, which is the case if the entire administered dose reaches systemic circulation.
• The bioavailability of drug is dependent on its dosage, absorption, metabolism and excretion.

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