Biotransformation

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Contents

Used for

biodegradation, bioremediation, catabolism

Broader Terms

metabolism

Related Terms

detoxification, drug metabolism, environmental contamination, protein degradation

Scope Note

series of chemical alterations of an exogenous compound which occur within a biological system, as by enzymatic activity.

Facts (generated by robot; please edit if you find it inaccurate)

  • Pharmacogenetics of Tamoxifen Biotransformation Is Associated With Clinical Outcomes of Efficacy and Hot Flashes Matthew P.
  • They provide evidence that sustained treatment with nitroglycerin in vivo is associated with reduced nitroglycerin biotransformation by ALDH-2 and that this abnormality in nitrate biotransformation is associated with increased mitochondrial formation of free radical oxygen species (Figure 1).
  • Kinetics of piribedil and effects on dopamine metabolism: hepatic biotransformation is not a determinant of its dopaminergic action in rats.
  • Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes.
  • Biotransformation is often called metabolism, although the latter term has a broader definition (see metabolism).

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