Bone development
From Health Encyclopedia
Contents |
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Broader Terms
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Narrower Terms
normal ossification, osteogenesis
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Related Terms
calcium metabolism, substantia spongiosa
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Scope Note
growth and development of bones from fetus to adult; includes two principal mechanisms of bone growth, which are growth in length of long bones at the epiphyseal cartilages, and growth in thickness by depositing new bone; see also OSTEOGENESIS.
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Facts (generated by robot; please edit if you find it inaccurate)
- Carpal and tarsal bone development is highly sensitive to three antiproliferative teratogens in mice.
- While chondrogenesis and endochondral ossification are relatively well studied, the intramembranous (dermal) bone development is very poorly understood.
- Bone development is regulated by conserved signalling pathways that are linked to multifunctional growth factors and their high affinity receptors.
- Janz said it is crucial for children to start early in developing strong, dense bones because the window for bone development is limited.
- Endochondral bone development is a multistep sequential cascade and the process must be operationally dissected.
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