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Coagulation factor X

Used for

autoprothrombin III, EC 3.4.21.6, prothrombase, prothrombinase, Prower factor, Stuart factor, thrombokinase

Broader Terms

clotting factor, serine proteinase

Facts (generated by robot; please edit if you find it inaccurate)

  • The structural gene for human coagulation factor X is located on chromosome 13q34.
  • The relative orientation of Gla and EGF domains in coagulation factor X is altered by Ca2+ binding to the first EGF domain.
  • Blood coagulation Factor X is a serine protease required for both the intrinsic and extrinsic pathways of coagulation.
  •  ; "The relative orientation of Gla and EGF domains in coagulation factor X is altere 1000 d by Ca2+ binding to the first EGF domain.
  • Coagulation factor X is activated by the extrinsic Xase complex composed of factor VIIa associated with the integral membrane protein tissue factor.
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