Cyclic peptide

From Health Encyclopedia

Contents 1 Used for 2 Broader Terms 3 Narrower Terms 4 Facts (generated by robot; please edit if you find it inaccurate)

Used for

IPSTYL, lanreotide

Broader Terms

peptide

Narrower Terms

actinomycin, cyclosporine

Facts (generated by robot; please edit if you find it inaccurate)

• The sequence of the cyclic peptide is derived from the arginine-rich motif of BIV Tat protein and contains all of the critical residues for RNA recognition.
• The structure(s) of a cyclic peptide is usually narrowly defined by the producing organism.
• While the predominant conformation of this cyclic peptide is 3-fold symmetric in the apolar solvent methylene chloride, an asymmetric structure is preferred in some polar solvents (water, dimethylsulfoxide).
• The results showed that the cyclic peptide is a better ligand for the 3 mAbs 125-F, 125-J and 125-K.
• It could be demonstrated that the above mentioned cyclic peptide is a specific inhibitor for this receptor, whereas platelet aggregation (aIIbP3 receptor) is only weakly inhibited (selectivity !).

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