DOPA
From Health Encyclopedia
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Facts (generated by robot; please edit if you find it inaccurate)
- Therapeutic use L-DOPA is used to replace dopamine lost in Parkinson's disease because dopamine itself cannot cross the blood-brain barrier where its precursor can.
- " As already mentioned, L-DOPA is often administered to Parkinson's patients because it increases the amount of dopamine that is synthesized in their brain.
- L-Dopa is controversial - Problem 1: Absorption.
- DOPA is formed in these proteins by post-translational hydroxylation of tyrosine residues.
- Therefore, the precursor L-dopa is administered, instead of dopamine.
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