Dibenamine

Use

The data set with dibenamine is in columns 3 and 4.
The edema-producing action of 5-hydroxytryptamine can be differentiated from the similar action of histamine by the use of specific antagonists; dibenamine is a 5-hydroxytryptamine antagonist and pyrilamine a histamine antagonist.
These data suggest, therefore, that Dibenamine is an active blocking agent for both epinephrine and norepinephrine whereas the imidazoline compounds, while qualitatively similar, are potent blocking agents for epineph- rine but are less active against norepineph- rine.
Dibenamine is another member of this class of compounds.
Dibenamine is an adrenergic blocking agent with very little antihistaminic activity, and it would not be expected to inhibit decidualization in this dose range if only antihistaminic activity were involved.

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