Digoxin
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- 943 Bioavailability ~75% Metabolism Hepatic (16%) Elimination half-life 36 hours Excretion ~70% renal unchanged Pregnancy category Category C Legal status POM (UK) Routes of administration oral, intravenous Digoxin is a cardiac glycoside extracted from the foxglove plant, digitalis.
- Digoxin is usually taken once a day.
- F a ctfile7 / 2 0 0 1 THE USE OF DIGOXIN The main indication for digoxin is permanent/persistent stable atrial fibrillation with a fast ventricular rate.
- PRECAUTIONS Use in Patients with Impaired Renal Function: Digoxin is primarily excreted by the kidneys; therefore, patients with impaired renal function require smaller than usual maintenance doses of digoxin (see DOSAGE AND ADMINISTRATION).
- Digoxin is an inotropic drug belonging to a class of drugs known as cardiac glycosides and was originally produced from the foxglove flower.
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