Dopamine transporter

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Contents

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Used for

dopamine uptake complex

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See for

DAT

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Broader Terms

membrane transport protein

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Related Terms

drug receptor, neurotransmitter transport

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Scope Note

sodium dependent transport protein, located on presynaptic terminals, involved in the uptake of dopamine; site at which cocaine exerts rewarding/ reinforcing effects.

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Facts (generated by robot; please edit if you find it inaccurate)

  • Bupropion occupancy of the dopamine transporter is low during clinical treatment.
  • The dopamine transporter is important for neural function because it removes excess dopamine from the synapse, effectively ending the signalling of the neurotransmitter.
  • "It shows that the dopamine transporter is not necessary for cocaine reward.
  • A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.
  • COM IN DEVELOPMENT SITE INDEX HOW TO USE THIS SITE Epilepsy NewsDopamine transporter is linked with methylphenidate response in ADHD January 13, 2006 Genomics & Genetics Weekly via NewsEdge Corporation : 2006 JAN 20 - (NewsRx.
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