Dystrophin
From Health Encyclopedia
Contents |
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Broader Terms
actin binding protein, muscle protein
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Related Terms
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Scope Note
large, structural, spectrin-like protein expressed in skeletal muscle; genetic defect is linked to Duchenne and Becker muscular dystrophy.
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Facts (generated by robot; please edit if you find it inaccurate)
- A novel dystrophin isoform is required for normal retinal electrophysiology.
- The se verity of symptoms correlates with the degree to which expression of dystrophin is impaired.
- 1995 Oxford University Press RESEARCH-ARTICLE A novel dystrophin isoform is required for normal retinal electrophysiology Vinita N.
- Only a shortened version of dystrophin is formed.
- The gene for DMD, found on the X chromosome, encodes a large protein - dystrophin.
- Home ABP A-Z Encyclopaedia Amoebae Protist Links Cytoskeleton Links Site Index Dystrophin A 410kd protein that connects the cortical actin cytoskeleton to a glycoprotein complex at the cell membrane of muscle and nerve cells.
- Dystrophin exon specific probes and X centromere in different colours for the same chromosome allows accurate interpretation of results.
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