Endocrine disrupting compound

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Contents

Used for

endocrine disruptor

Broader Terms

chemical

Related Terms

arsenic, cadmium, environmental toxicology, furan, halobiphenyl /halotriphenyl compound, hormone analog, insecticide biological effect, lead, mercury, pesticide biological effect, phenone

Scope Note

exogenous agent that mimics endogenous hormones, or interferes with the production, release, transport, metabolism, binding, action or elimination of natural hormones in the body responsible for the maintenance of homeostasis and the regulation of developmental processes.

Facts (generated by robot; please edit if you find it inaccurate)

  • The hyperlink below refers you to a chapter from "Generations at Risk," and focuses on Endocrine Disrupting Compounds (EDCs) and their varied effects on humans and the environment.
  • The test is intended to expose all four critical life stages (in ovo, juvenile, subadults, and adults) to assess any adverse effects associated with a pu- tative endocrine disrupting compound quantitatively.
  • New research has demonstrated that endocrine disrupting compounds violate this assumption, that there is literally no threshold of effect for an endocrine disrupting compound when it is added to a hormone system that is already active.
  • , altered phenotypes were noted in up to 4 generations of offspring of pregnant rats exposed to endocrine disrupting compounds during the period of gestation corresponding to gonadal sex determination.

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