Fatty acid synthase

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Contents

Used for

EC 2.3.1.85

Broader Terms

acyltransferase

Narrower Terms

acyl carrier protein

Related Terms

polyketide synthase

Scope Note

EC 2.3.1.85; animal enzyme is a multi-functional protein catalyzing the reactions of EC 2.3.1.38, EC 2.3.1.39, EC 2.3.1.41, EC 1.1.1.100, EC 4.2.1.61, EC 1.3.1.10, and EC 3.1.2.14.

Facts (generated by robot; please edit if you find it inaccurate)

  • Fatty acid synthase is the only enzyme that can generate fats within the cell; all other fat comes from the diet.
  • Evidence that the coenzyme A requirement for avian fatty acid synthase is not for the termination reaction.
  • Fatty acid synthase is required for the proliferation of human oral squamous carcinoma cells.
  • ARTICLE Fatty acid synthase is a potential molecular target for the chemoprevention of breast cancer Suying Lu and Michael C.
  • Fungal fatty acid synthase is a huge barrel-shaped molecular assembly with two reaction chambers, each containing three full sets of active sites separated by large distances across which the substrates have to be shuttled during the reaction cycle.

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