Gene deletion mutation

Broader Terms

gene mutation

Facts (generated by robot; please edit if you find it inaccurate)

• For example HbH disease is usually caused by the deletion of three α-globin genes (--/-α) as a result of the inheritance of a single gene deletion mutation (-α/) from one parent and a two-gene deletion mutation (--/) from the other parent.
• For example HbH disease is usually caused by the deletion of three -globin genes (--/-) as a result of the inheritance of a single gene deletion mutation (-/) from one parent and a two-gene deletion mutation (--/) from the other parent.
• Conclusion These results suggest a link of ATM gene deletion/mutation with rhabdomyosarcoma, and since ATM kinase is a crucial regulatory protein in DNA damage repair signaling pathway, and ATM deletion/mutation may contribute to pathogenesis of rhabdomyosarcoma.
• Measurement of the relative growth rate of each yeast gene-deletion strain, over a period of several cell division generations, can be used to identify both qualitative and quantitative functions of each gene deletion mutation.