Genetic inhibitor

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gene induction /repression, transcription factor

Facts (generated by robot; please edit if you find it inaccurate)

  • When the genetic inhibitor of calcineurin was "turned on," Winder said, they found enhanced long-term potentiation (LTP), a lasting change in neuronal communication thought to reflect the cellular changes that underlie learning and memory.
  • Other pharmacological and genetic inhibitors of NF-B also stimulate muscle differentiation in vitro.
  • Using a genetic inhibitor, termed Mu inhibitor, we have developed a population of 43,776 plants containing stabilized Mu insertions.
  • v 5-azacytidine is a genetic inhibitor that has been shown to induce cardiomyogenic differentiation in culture.
  • Activatory effects of c-Jun/AP-1 dimers on p21WAF1/Cip1 promoter as well as inhibitory effects of c-Jun genetic inhibitor, TAM67 suggest the direct engagement of c-Jun/AP-1 in CsA-induced p21WAF1/Cip1 expression, possibly through interactions with Sp1 transcription factor.

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