Glycosylation
From Health Encyclopedia
Contents |
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Broader Terms
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Narrower Terms
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Related Terms
glycoprotein biosynthesis, glycosyltransferase, posttranslational modification
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Scope Note
chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins.
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Facts (generated by robot; please edit if you find it inaccurate)
- Mucin core O-glycosylation is modulated by neighboring residue glycosylation status.
- 2000 N-linked Glycosylation Is Required for Optimal Function of Kaposi's Sarcoma Herpesvirus–encoded, but Not Cellular, Interleukin 6 Charles S.
- Glycosylation is Critical for Normal Development and Differentiation (A) Genetic elimination or partial abrogation of expression of each of the major classes of glycans has been shown to be lethal during murine embryogenesis.
- Posttranslational, reversible O-glycosylation is stimulated by high glucose and mediates plasminogen activator inhibitor-1 gene expression and Sp1 transcriptional activity in glomerular mesangial cells.
- uk Prion proteins that are normal cellular components or involved in pathology can vary little or not at all in primary amino acid sequence, but their glycosylation is different, e.
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