GnRH

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gonadotropin releasing factor

Facts (generated by robot; please edit if you find it inaccurate)

  • Since GnRH acts as a neurotransmitter and because the pulsatile secretion of GnRH is crucial for the proper responsiveness of the pituitary gland, an efficient mechanism for rapid clearance of GnRH is necessary.
  • Women who respond poorly to Pergonal alone often do better if GnRH is used as well.
  • GnRH is produced by the hypothalamus, a major organ in the brain.
  • Now research is focusing on what each GnRH is doing, and whether one is more important that the others.
  • Pituitary synaptic protein SNAP-25 sensitive to GnRH is necessary for LH release.

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