Heme oxygenase
From Health Encyclopedia
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Scope Note
EC 1.14.99.3.
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Facts (generated by robot; please edit if you find it inaccurate)
- Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti-proliferative role.
- Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat.
- First, biliverdin is the sole precursor of bilirubin and heme oxygenase is a potential target for the control of hyperbilirubinemia in neonatal children and in a number of hereditary disorders.
- Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.
- Under normal physiological conditions, the activity of heme oxygenase is highest in the spleen, where old erythrocytes are sequestrated and destroyed.
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