Hemolysin
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Facts (generated by robot; please edit if you find it inaccurate)
- alpha-hemolysin is exported by the bacterium Staphylococcus aureus in the form of a water soluble protein (Mr 33,2 kDa).
- Escherichia coli hemolysin is released extracellularly without cleavage of a signal peptide.
- Membrane insertion of Escherichia coli alpha-hemolysin is independent from membrane lysis.
- The analysis of the DNA sequence (GenBank accession number AY157998) showed that the hemolysin is homologous with aerolysin produced by Aeromonas hydrophila.
- Based on microscopy studies, we propose that alpha-hemolysin is required for cell-to-cell interactions during biofilm formation.
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