Hensin

From Health Encyclopedia

Use

scavenger receptor

Facts (generated by robot; please edit if you find it inaccurate)

• Although these cells synthesize and secrete hensin, it is not retained in the ECM, but rather, hensin is present in a large number of intracellular vesicles.
• Hensin is secreted as a monomer which is then polymerized in the extracellular environment by a complex process requiring at least three other proteins.
• The novel protein hensin is expressed in the extracellular matrix (ECM) surrounding adapting HCO3-secreting intercalated cells (B-ICs) and plays a key role in this adaptation.
• Hensin is a member of the scavenger receptor cysteine rich (SRCR) family (6).
• Hensin is secreted as a monomer, and activation of the cell induces two activities that convert it to a dimer by folding and into a fiber by bundling of the folded dimers by galectin 3.

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