Immediate early protein

From Health Encyclopedia

Contents 1 See for 2 Broader Terms 3 Narrower Terms 4 Related Terms 5 Scope Note 6 Facts (generated by robot; please edit if you find it inaccurate)

See for

ICP47, IE12

Broader Terms

DNA binding protein

Narrower Terms

connective tissue growth factor

Related Terms

regulatory gene, virus protein

Scope Note

proteins that regulate the expression of genes of other kinetic classes.

Facts (generated by robot; please edit if you find it inaccurate)

• The immediate-early protein is also self-regulatory; the presence of the functional immediate-early protein represses the transcription of its RNA.
• The acidic domain of the human cytomegalovirus UL37 immediate early protein is dispensable for its transactivating activity and localization but is not for its synergism.
• The proteins in this family are poorly characterized, but an investigationhas indicated that the immediate early protein is required the down-regulation of MHC class I expression in dendrit: 2 Genes [ Show Summary ] [Show Protein Alignments ] GeneProductIsoforms CountUniq.
• In the further characterization of the KSHV ORF45 protein, we demonstrated that this immediate-early protein is a phosphorylated and cytoplasmic protein.
• (1996) Activation of the Epstein–Barr virus DNA polymerase promoter by the BRLF1 immediate-early protein is mediated through USF and E2F J.

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