Immediate hypersensitivity
From Health Encyclopedia
Contents |
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Used for
antibody hypersensitivity, humoral hypersensitivity, type I hypersensitivity
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Broader Terms
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Narrower Terms
anaphylaxis, Arthus phenomenon, atopy, eczema, histamine release, immune complex disease, respiratory hypersensitivity
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Related Terms
airborne allergen, leukotriene
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Scope Note
hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
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Facts (generated by robot; please edit if you find it inaccurate)
- Immediate hypersensitivity is mediated by IgE.
- [Immediate hypersensitivity is rarely implicated in drug induced urticaria]Cousin F, Catelain A, Philips K, Favier B, Queuille E, Nicolas JF.
- fromIndian J Physiol Pharmacol -Jul 2001 -M Lakshmana, M Rafiq [Ski 8 n prick 1ff8 test of immediate hypersensitivity in a selected Chilean pediatric population sample]: Skin prick test (SPT) of immediate hypersensitivity is a main instrument in the diagnosis of allergy.
- The development of immediate hypersensitivity is a two-step process (Click Phase 1/Phase 2 on theimage below) Phase 1:Sensitisation phase - When the immune system of atopic individuals is first exposed to an allergen, B lymphocytes produce an excess ofIgE antibodies.
- Sensitivity to mite antigens is found in 20% to 60% of patients when immediate hypersensitivity is evaluated by the detection of specific IgE antibodies and prick tests, and in 30% to 50% of patients when delayed hypersensitivity is studied by patch testing.
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