Immunodeficient mouse model

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The immunodeficient mouse model is an established system for investigation of immature human AML cells19-21 and might serve as a useful tool to investigate the effect of DT-GM-CSF to AML cells with long-term repopulating capacity.
While the immunodeficient mouse model is a suitable screen and could be applicable to other cancers, Kim voiced concerns about the relatively short follow-up period in light of the naturally short life span of immunodeficient mice.
501 Spring 2006 Choosing an Immunodeficient Mouse Model Immunodeficient mouse models, particularly severe combined immunodeficient (Prkdcscid and Rag1null) mice, are very useful models for immunology, infectious disease, cancer, stem cell biology, and other research.
A novel immunodeficient mouse model--RAG2 x common cytokine receptor gamma chain double mutants--requiring exogenous cytokine administration for human hematopoietic stem cell engraftment.
A new immunodeficient mouse model for human myoblast transplantation.
Putative anticryptosporidial agents tested with an immunodeficient mouse model.
Cg-Rag1 Prf1/SzJ - A New Immunodeficient Mouse Strain Supporting Enhanced Human Hematolymphoid Cell Engraftment Immunodeficient mouse models have been instrumental in helping us understand the functions of human hematopoietic stem cells (HSC) and mature lymphoid cells in vivo.

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