Immunological synapse

See

antigen presentation

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” What Chakraborty and his group found when they ran simulations on their computer cluster is that the immunological synapse is indeed the site of enhanced T cell signaling but these triggered T cell receptors are subject to degradation over an extended period of time.
Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength.
Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1.
In 2003, his computational models indicated that the immunological synapse is responsible for intense but self-limited T cell signaling.
; Kardar, Mehran The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T Cells and antigen presenting cells (APCs) during recognition.

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This page was last modified on 26 May 2006, at 17:24. This page has been accessed 125 times.

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