Immunoregulation

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Contents

Used for

idiotype regulatory network, immune modulation, immunologic reactivity control

See for

immunogenic, immunoreaction, immunoreactivity

Broader Terms

immunology

Narrower Terms

antigen presentation, immune tolerance /unresponsiveness, immunologic memory

Related Terms

antiidiotype antibody, immune response, immunogenetics

Scope Note

various processes by which antibodies may regulate immune responses; at a simple level, secreted antibody neutralizes the antigen with which it reacts thus preventing further antigenic stimulation of the antibody producing clone; at a more complex level, anti-idiotype antibodies can be shown to develop against the first antibodies in some cases and perhaps further anti-idiotype antibodies against them; this is the major concept of the immunological network theory.

Facts (generated by robot; please edit if you find it inaccurate)

  • Antibody-specific immunoregulation is restricted by the major histocompatibility gene complex.
  • Nevertheless, information regarding the effect of steroid-based oral contraception on humoral immunoregulation is limited.
  • This form of immunoregulation is the dominant means utilized by the immune system to reach a harmony between reciprocal response processes in order to ensure adequate host defense with minimal host detriment.
  • It is now apparent, that the ultimate center of immunoregulation is the hypothalamus, which has the power to control immune and inflammatory reactions both by neural and endocrine mechanisms.
  • Multi-component immunoregulation is known to be achieved with the help of a group of products approaching their natural concentration in the body, rather than with the help of just one product extracted in isolation.

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