In utero transplantation

From Health Encyclopedia

Contents 1 Used for 2 See for 3 Broader Terms 4 Facts (generated by robot; please edit if you find it inaccurate)

Used for

prenatal transplantation

See for

intrauterine transplantation

Broader Terms

embryo /fetus surgery, transplantation

Facts (generated by robot; please edit if you find it inaccurate)

• In utero transplantation is a new technology that may provide non-toxic treatment for congenital disorders.
• The documentation of long-term multilineage human chimerism in the second-generation recipients represents definitive evidence that chimerism after in utero transplantation is secondary to engraftment of true HSC and that it can, at least potentially, persist for the lifetime of the recipient.
• donor reactivity prior to in utero transplantation is likely to potentiate more favorable outcomes.
• Experiments on the mouse, sheep and rhesus monkey have indicated that in utero transplantation is feasible.
• But the use of in utero transplantation is limited to prenatally diagnosed hereditary disorders, and because it must be performed early in gestation, there is a risk of aborting the pregnancy.

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