Kindling

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Contents

Broader Terms

brain electrical activity

Related Terms

epilepsy

Scope Note

experimental animal model of epilepsy in which a subconvulsive electrical stimulus is repeatedly applied to limbic or other brain structures, eventually producing a heightened susceptibility to generalized seizures.

Facts (generated by robot; please edit if you find it inaccurate)

  • Amygdalar kindling is associated with elevated zinc concentration in the cortex and hippocampus of rats.
  • Enhancement of recurrent inhibition by angular bundle kindling is retained in hippocampal slices.
  • As a result of many decisions and much misinformation generated during the last forty years, even the next generation of commercial reactors are slated to be reactors whose kindling is so well dispersed that it does a poor job of getting the more abundant U-238 to produce heat.
  • As such, kindling is one of the best models of secondary generalized temporal lobe epilepsy, and much of our understanding of how epilepsy works comes from the study of kindling.
  • Kindling is believed to be one of the leading explanations for this.

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