LDL receptor

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low density lipoprotein receptor

Facts (generated by robot; please edit if you find it inaccurate)

• Characteristics: The LDL receptor is a cell surface glycoprotein of 839 aminoacids.
• Brown and Goldstein have used modern molecular biology techniques to show that the LDL-receptor is a glycoprotein located in the cell membrane.
• The LDL receptor is the major pathway for beta-VLDL uptake by mouse peritoneal macrophages.
• Lectin-like Ox-LDL receptor is expressed in human INT-407 intestinal cells: involvement in the transcytosis of pancreatic bile salt-dependent lipase.
• We began with the discovery of the LDL receptor, a cell surface protein that binds LDL particles and removes them from blood.
• LDL-receptor-related proteins in Wnt signal transduction.
• LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development.

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