Leydig cell

From Health Encyclopedia

See for

interstitial cell

Broader Terms

cell, testis

Facts (generated by robot; please edit if you find it inaccurate)

• Effect of erythropoietin on Leydig cell is associated with the activation of Stat5 pathway.
• In fact, the Leydig cell is known to possess an estrogen receptor that binds estradiol in the classic manner.
• It is worth noting, however, that lipid droplet distribution in the GnRH-null adult Leydig cell is similar to that of the normal adult Leydig cell although the lipid droplets are larger and more frequent.
• Another supportive evidence which suggests its involvement in regulation of steroidogenesis in Leydig cell is the fact that addition of 150 g of protein from cytosol of adrenal of an adult male rat which is steroidogenically very active was not effective in inhibiting testosterone production.
• All of the available evidence suggests that the action of the LHRH-like factor on the Leydig cell is inhibitory, and it may mediate some or all of the negative effects on the Leydig cell of LH and hCG.

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